Clinical Efficacy of Rituximab Combined with CHOP Regimen Sequential or Non-Sequential Local Radiotherapy in Diffuse Large B-Cell Lymphoma

نویسندگان

چکیده

To probe the clinical efficacy of rituximab combined with cyclophosphamide, adriamycin, vincristine together prednisone regimen sequential or non-sequential local radiotherapy in patients stage III-IV diffuse large B-cell lymphoma. The data 126 high-risk lymphoma First Affiliated Hospital Hainan Medical University from January 2018 to December 2021 were retrospectively analyzed. Among them, group adopted regimen, addition and treated group. short-term long-term efficacy, adverse reactions immunoglobulin levels compared these three groups. In comparison group, total effective rate was elevated whole increased relative Spearman correlation analysis unveiled that negatively correlated serum M level after 4 courses 6 treatment. Rituximab is therapy, which can significantly promote high safety.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Efficacy of rituximab combined with CHOP for treating patients with diffuse large B-cell lymphoma

BACKGROUND This study aimed to evaluate the efficacy and safety of rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for treating patients with diffuse large B-cell lymphoma (DLBCL). METHODS A total of 144 patients with DLBCL were randomly divided into intervention group and control group, 72 patients in each group. The patients in the control group r...

متن کامل

A Case Report of a Metastatic Primary Gastric Lymphoma; Diffuse Large B-Cell or Burkitt Lymphoma?

Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

متن کامل

A Case Report of a Metastatic Primary Gastric Lymphoma; Diffuse Large B-Cell or Burkitt Lymphoma?

Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

متن کامل

Addition of rituximab to the CHOP regimen has no benefit in patients with primary extranodal diffuse large B-cell lymphoma

BACKGROUND The addition of rituximab to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy (R-CHOP) has significantly improved clinical outcomes for patients with diffuse large B-cell lymphoma (DLBCL). However, new predictors of patient response to R-CHOP have not been established. We aimed to evaluate the impact of R-CHOP compared with CHOP in patients with DLBCL an...

متن کامل

Additional rituximab-CHOP (R-CHOP) versus involved-field radiotherapy after a brief course of R-CHOP in limited, non-bulky diffuse large B-cell lymphoma: a retrospective analysis

BACKGROUND Standard treatment for stage I or non-bulky stage II diffuse large B-cell lymphoma (DLBCL) has been either a brief course of chemotherapy plus involved-field radiotherapy (IFRT) or prolonged cycles of chemotherapy. The introduction of rituximab has necessitated re-evaluation of the treatment for limited disease (LD) DLBCL. METHODS Thirty-nine LD DLBCL patients (median age, 52 years...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2023

ISSN: ['0250-474X', '1998-3743']

DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.642